Four years after No Way Home, Peter lives alone, erased from the lives of those he loves. Fully devoted to protecting New York, mounting pressure triggers a physical evolution that threatens his existence as a powerful new threat emerges.

The story follows Odysseus on his epic journey home after the Trojan War, highlighting his encounters with Polyphemus, the Sirens, and Circe, culminating in a heartfelt reunion with his wife, Penelope.