A directionless Kara Zor-El, also known as Supergirl, questions her place in the universe now that her cousin Kal-El no longer needs her. On the verge of giving up, she's approached by Ruthye Marye Knoll, a determined young warrior seeking justice for her father's death and the destruction of her home. Together, they set out on a cosmic quest that reignites Supergirl’s sense of purpose.